The Apostle Paul saw the Holy Spirit much differently than many of us do. While many of us see the Holy Spirit as a sort of adviser, Paul saw Him as his Master. While many of us see the Holy Spirit as a supplement to our faith, Paul sees him as central.
A great example of this is in Acts 20, where Paul says that he is literally "chained to" or "bound to" the Holy Spirit, even when the Spirit leads him to places where there will be hardship and suffering.
It's obvious that the majority of us don't submit to the Spirit in this way, but we are invited deeper into submission. We are all on a journey of relying more and more on the Spirit, from being curious about him, to being led by him, to being bound to him. And it is through being bound to the Spirit that God can use hardship and suffering in our lives to produce power in us to reach the world.