Pastor Eric Phillips preaches on shaking off negativity and toxic influences by trusting God in adversity. Drawing from the story of Paul in Acts 28, he highlights the need for discernment and relying on God's strength to overcome challenges. He encourages the congregation to identify harmful influences as well as to be willing to help others despite risks. Ultimately, he emphasizes the power of God's healing and restoration, reminding them to keep faith in the midst of trials.