Pastor Lonnie Hardy's sermon "Pop Up's" focuses on persecution and personal struggles believers face, urging them to stand strong, possess their souls, and surrender to God. He highlights challenges from external events as "pop ups" and emphasizes the need for believers to control their minds, wills, and emotions. Pastor Hardy calls on the Church to confront weaknesses, transform to align with God's will, and mature through facing struggles. Finally, he invites individuals to commit to Jesus and seek growth in their relationship with Him.